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Am J Forensic Med Pathol ; 41(4): e61-e63, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-791494

ABSTRACT

The autopsy findings for 3 cases of SARS-(CoV-2) pneumonia-related deaths are reported with pulmonary histology and immunohistochemistry findings. In 2 cases (cases 1 and 2), the time interval from presentation to death was approximately 1 week, whereas for case 3, the time interval from presentation to death was hours. Case 1 and case 2 presented with shortness of breath, cough, and flu-like symptoms. The decedent from case 3 died shortly after presenting to a local emergency room with high fever, chest and abdominal pain, and shortness of breath. All 3 cases had 1 or more comorbidities. The postmortem interval for cases 1 and 2 was 2 weeks as they died at sea and were stored on board within the respective cruise ships' refrigeration units, whereas case 3 was examined within 24 hours of death. The autopsies were conducted at the Miami-Dade County Medical Examiners Department under routine infectious precautions. Salient clinical history and autopsy findings are summarized. Microscopic examination revealed pneumonia with associated atypical endovascular cells.


Subject(s)
Betacoronavirus , Coronavirus Infections/pathology , Pneumonia, Viral/pathology , Adult , Autopsy , COVID-19 , Cardiomegaly/complications , Cardiomegaly/pathology , Circle of Willis/pathology , Comorbidity , Coronary Artery Disease/complications , Coronary Artery Disease/pathology , Coronavirus Infections/complications , Diabetes Complications/pathology , Fatal Outcome , Female , Humans , Hyperlipidemias/complications , Hyperlipidemias/pathology , Lung/pathology , Male , Middle Aged , Nasopharynx/virology , Obesity/complications , Obesity/pathology , Pandemics , Pneumonia, Viral/complications , Pulmonary Edema/complications , Pulmonary Edema/pathology , SARS-CoV-2 , Tobacco Use/pathology
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